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ED For Him Guide

What Causes Erectile Dysfunction?

An erection depends on blood vessels, nerves, hormones, brain signals and sexual stimulation working together. A problem in any part of that system can contribute to ED.

Physical causes

  • Heart and blood-vessel disease
  • Diabetes
  • High blood pressure
  • Obesity
  • Kidney disease
  • Neurologic conditions or nerve injury
  • Low testosterone or thyroid disorders
  • Peyronie’s disease or pelvic injury/surgery

Medication-related causes

Some antidepressants, blood-pressure medicines, antihistamines and other medications can contribute. Never stop a prescribed medicine on your own; ask the prescriber whether an alternative is appropriate.

Psychological and relationship factors

Stress, depression, anxiety and performance anxiety can all affect erections, even when physical health is otherwise good.

Lifestyle contributors

Smoking, heavy alcohol use, recreational drugs, inactivity and poor cardiometabolic health can worsen erectile function.

Sources